Cri du coeur

Cri du chat syndrome.

Since the description of the first three cases of the 'cri du chat' syndrome by Lejeune, Lafourcade, Berger, Vialatte, Boeswillwald, Seringe, and Turpin (1963), 12 patients have been reported on in whom part of the short arms of a chromosome in the 4-5 group were absent (Lejeune, Lafourcade, de Grouchy, and Berger, 1964b; Punnett, Carpenter, and DiGeorge, 1964; Book, Atkins, and Santesson, 1963...

Cri du Chat syndrome

The Cri du Chat syndrome (CdCS) is a genetic disease resulting from a deletion of variable size occurring on the short arm of chromosome 5 (5p-). The incidence ranges from 1:15,000 to 1:50,000 live-born infants. The main clinical features are a high-pitched monochromatic cry, microcephaly, broad nasal bridge, epicanthal folds, micrognathia, abnormal dermatoglyphics, and severe psychomotor and m...

Cri-du-chat syndrome

Three cases of cri du chat syndrome with varying ages of presentation are compared and contrasted to highlight the clinical features and evolution of the phenotype with time.

Commentary: Facts, opinions and affaires du coeur.

It is now over 30 years since Michael Marmot began his comment article with the provocative quotation ‘. . . these are the opinions on which I base my facts . . .’. Here Marmot identifies a central tension found in many branches of the sciences: namely, how is it possible to evaluate and choose between the competing theories or hypotheses that often seek to explain the same phenomena? A concern...

Placement du coeur d’un réseau mobile autonome